Álvaro García Casas Biomedical Engineering  •  UC3M / Georgia Tech
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Engineering Projects

A selection of engineering projects across mechatronics, electrophysiology, biosignal instrumentation, computational fluid mechanics, medical AI, and cellular therapeutics.

Mechatronics & Product Design 2026

Smart Stove Safety Knob

CREATE-X Startup Accelerator • Georgia Institute of Technology

Fail-safe retrofit device that automatically shuts off unattended stovetops. Spring-loaded ratchet mechanism stores mechanical energy when user turns knob ON; if PIR detects no presence, dual servos release the spring — driving the knob back to OFF. Works on gas & electric, tool-free install, sub-$50 BOM.

Product Design Customer Discovery CAD Electronics PCB Design App Development 3D Printing Regulatory Strategy
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Smart Stove Safety Knob
Mechatronics & Product Design

Smart Stove Safety Knob

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Instrumentation & Biosignals 2025

Wearable Forearm Sensor Cuff: Tremor & Autonomic Stress Biomarkers

Georgia Institute of Technology

Continuous forearm sensor cuff integrating surface EMG and GSR to quantify sympathetic stress impact on neurogenic tremor. Validated across 10 patients (5 trials each), demonstrating significant inverse correlation (p = 0.041, R² = 0.4266).

Biosignal Acquisition Surface EMG & GSR Hardware Prototyping Digital Signal Processing (DSP) In-Vivo Clinical Trials Embedded Telemetry
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Wearable Forearm Sensor Cuff: Tremor & Autonomic Stress Biomarkers
Instrumentation & Biosignals

Wearable Forearm Sensor Cuff: Tremor & Autonomic Stress Biomarkers

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Electrophysiology & Vascular Biomechanics 2026

Cardiovascular Hemodynamics & Electromechanical Waveform Profiling

Georgia Institute of Technology

Dual-channel synchronized biopotential (Lead II) and infrared photoplethysmography (PPG) profiling. Quantified pre-ejection latency, autonomic vasomotor response, and age-dependent arterial stiffening (SI: 5.61 → 12.80 m/s) across subjects aged 9–86.

Cardiovascular Hemodynamics ECG & PPG Acquisition Pulse Wave Velocity (PWV) Arterial Biomechanics Signal Filtering Data Analytics
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Cardiovascular Hemodynamics & Electromechanical Waveform Profiling
Electrophysiology & Vascular Biomechanics

Cardiovascular Hemodynamics & Electromechanical Waveform Profiling

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Medical AI & Computer Vision 2026

Medical Image Detection & Classification (RSNA Benchmark)

Radiological Society of North America (RSNA)

Deep Learning architectures (Vision Transformers & ConvNeXt) in PyTorch for automated multi-label detection of 12 knee anomalies in volumetric MRI, achieving 0.936 Macro ROC-AUC benchmark.

Deep Learning Computer Vision PyTorch Medical Imaging (DICOM) Vision Transformers Model Evaluation (ROC-AUC)
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Medical Image Detection & Classification (RSNA Benchmark)
Medical AI & Computer Vision

Medical Image Detection & Classification (RSNA Benchmark)

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Computational Modeling & Fluid Mechanics 2025

Pulsatile Womersley Flow Simulation in Carotid Geometry

Universidad Carlos III de Madrid

Numerical resolution of Navier-Stokes for unsteady pulsatile flow across Womersley numbers (0.1 to 30), validating against physical pulsatile flow experiments.

Computational Fluid Dynamics (CFD) Hemodynamic Modeling Navier-Stokes Solvers Numerical Simulation MATLAB Experimental Validation
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Pulsatile Womersley Flow Simulation in Carotid Geometry
Computational Modeling & Fluid Mechanics

Pulsatile Womersley Flow Simulation in Carotid Geometry

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Cellular Engineering & Oncology Therapeutics 2026

Dual-Pathway Targeted Cytotoxicity in Glioblastoma (U87EGFP)

Georgia Institute of Technology

In vitro oncology research evaluating ferroptotic (Erastin) and pro-oxidative (Ursolic Acid) dual-pathway cytotoxicity in U87EGFP glioblastoma. Quantified dose-response curves (IC₅₀ = 0.50 mM), additive tumor kill (~40%), and apoptotic morphology via 96-well spectrophotometry.

Cell Culture (BSL-2) In Vitro Assays Targeted Oncology Dose-Response Modeling Microplate Spectrophotometry Translational Research
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Dual-Pathway Targeted Cytotoxicity in Glioblastoma (U87EGFP)
Cellular Engineering & Oncology Therapeutics

Dual-Pathway Targeted Cytotoxicity in Glioblastoma (U87EGFP)

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